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Sporadic Creutzfeldt-Jakob Disease with RapidCognitive Decline and Cortical Ribboning: A Case Report

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Prompt recognition of characteristic MRI patterns is crucial for diagnosing sporadic CJD.
Cerebral imaging and CSF biomarkers significantly support the diagnosis of neurodegenerative disorders.
Early and accurate diagnosis of CJD can enhance patient management and counseling options.
The role of tau protein and other biomarkers can be pivotal in cases where conventional tests yield ambiguous results.

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Case report highlights cognitive decline and cortical ribboning in a CJD patient, suggesting a multimodal diagnostic approach.

PRICOPE et al. (2025) studied this question.

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