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October 1, 2025BiomoleculesOpen Access

Pharmacological Potential and Mechanisms of Bisbenzylisoquinoline Alkaloids from Lotus Seed Embryos

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This review discusses bisbenzylisoquinoline alkaloids' therapeutic potential in chronic diseases, highlighting their mechanisms and actions.

Lotus seed alkaloids exhibit significant antitumor, anti-inflammatory, and neuroprotective effects, indicating their therapeutic potential.
The alkaloids modulate key processes like oxidative stress and cytokine regulation, which are crucial in chronic disease pathways.
In-depth analysis reveals their mechanisms include apoptosis regulation and metabolic modulation across various disease models.
Preclinical studies showcase their diverse pharmacological activities, laying groundwork for clinical applications in treating acute and chronic diseases.

Liu et al. (2025) studied this question.

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This review discusses bisbenzylisoquinoline alkaloids' therapeutic potential in chronic diseases, highlighting their mechanisms and actions.