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October 1, 2025Medical Journal of BabylonOpen Access

The Relationship of Circulatory miRNA-21 Expression with IL-15 Level in Celiac Disease Patients in Karbala Province

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Authors

RARiyam Ahmed Shehab Al-JanabiAAAngham Jasim Mohammed Ali

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Overview

Observational analysis reveals elevated IL-15 and miRNA-21 in celiac disease patients, suggesting potential biomarkers.

Key Points

  • IL-15 levels were significantly higher in patients with celiac disease compared to healthy controls.
  • miRNA-21 expression was also markedly increased in celiac disease patients, indicating its potential as a biomarker.
  • The receiver operating characteristic curve for miRNA-21 indicated high sensitivity and specificity for diagnosing celiac disease.
  • Celiac disease prevalence was noted to be higher among females than males among the diagnosed patients.

Cite This Study

Al-Janabi et al. (2025) studied this question.

synapsesocial.com/papers/68dd9537fe798ba2fc499638https://doi.org/10.4103/mjbl.mjbl_411_24
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  1. 1Epigenetic Mechanisms of Genes Influencing Immune Response in Patients with Celiac Disease2024 · 1 citations
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  4. 4miR-155 and miR-21 as Diagnostic and Therapeutic Biomarkers for Ulcerative Colitis: There Is Still a Long Way to Go2024 · 9 citations
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