Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 2, 2025Journal of Neurology Neurosurgery & Psychiatry

Home-based EXergames To impRovE cognitive function in MUltiple Sclerosis (EXTREMUS)

View Full Paper
Ask AI
Bookmark
Share

Authors

LPLuca ProsperiniATAndrea TacchinoSRSerena Ruggieri

Discussion

Loading...

Member takes

Overview

Randomized trial shows cognitive improvements using exergames in MS patients, indicating potential benefits over sham intervention.

Key Points

  • Exergames significantly improved cognitive function in patients with multiple sclerosis.
  • At week 8, exergames showed an adjusted mean difference of 4.3 points on the SDMT compared to sham intervention.
  • The study utilized a three-arm, randomised, rater-blinded design with a sham-controlled trial.
  • Exergames offer a standalone approach to enhancing cognitive and motor dysfunctions in MS, but long-term benefits remain inconclusive.

Cite This Study

Prosperini et al. (2025) studied this question.

synapsesocial.com/papers/68de68ea83cbc991d0a215eahttps://doi.org/10.1136/jnnp-2025-336609
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of simultaneous aerobic exercise and cognitive training in persons with subjective cognitive decline residing in Minnesota: study protocol for randomized controlled trial of the Exergames TeleHealth Study2026
  2. 2PEMOCS: Evaluating the effects of a concept-guided, PErsonalised, MOtor-Cognitive exergame training on cognitive functions and gait in chronic Stroke—study protocol for a randomised controlled trial2024 · 6 citations
  3. 3The Effects of Exergame Telerehabilitation in Persons With Subjective Cognitive Decline2024 · 4 citations
  4. 4Exergaming and cognitive functions in people with mild cognitive impairment and dementia: a meta-analysis2024 · 37 citations
  5. 5Dual‑task exergaming to enhance motor and cognitive function in chronic stroke: a prospective, assessor-blinded, parallel group randomized controlled trial2026 · 1 citations