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October 1, 2025

Figure S1 from Development of Multivalent FAP-Targeted Small Molecule–Drug Conjugates with Tailored MMAE Release Kinetics

Matilde Bocci Lucrezia Principi Dario Neri Samuele Cazzamalli Ettore Gilardoni Andrea Galbiati

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Key Points

The study highlights the development of small molecule–drug conjugates with efficient release kinetics associated with MMAE.
FAP-targeted drug conjugates are designed to enhance therapeutic efficacy by tailoring release kinetics of the drug.
Chemical structures of previously described compounds inform the rational design and effectiveness of drug conjugates.
Understanding drug release kinetics may enable better targeting strategies, improving therapeutic outcomes.

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Implication

Chemical structures detail the design of FAP-targeted drug conjugates, indicating specific release kinetics.

Abstract

Chemical structures of the previously described compounds.

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Cite This Study

Bocci et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a219aa https://doi.org/10.1158/1535-7163.30255515

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Information from Development of Multivalent FAP-Targeted Small Molecule–Drug Conjugates with Tailored MMAE Release Kinetics2025
2Figure S2 from Development of Multivalent FAP-Targeted Small Molecule–Drug Conjugates with Tailored MMAE Release Kinetics2025
3Figure S6 from Development of Multivalent FAP-Targeted Small Molecule–Drug Conjugates with Tailored MMAE Release Kinetics2025
4Data from Development of Multivalent FAP-Targeted Small Molecule–Drug Conjugates with Tailored MMAE Release Kinetics2025
5Figure S4 from Development of Multivalent FAP-Targeted Small Molecule–Drug Conjugates with Tailored MMAE Release Kinetics2025