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October 1, 2025

Figure S1 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors

Eléonore Weber-Delacroix Marylou Panouillot Marie Laviron François Lanthiez Tristan Philippe Sandrine Barthélémy Solène Fastenackels Armanda Casrouge Benoı̂t L. Salomon Ingrid Sassoon Jérémy Baudhuin Ilaria Onorati Marianne Kambouchner Nahla Cucherousset Christophe Combadière Boris Duchemann Marie‐Caroline Dieu‐Nosjean Alexandre Boissonnas

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Key Points

Chemotherapy alters the myeloid landscape in lung tumors, with regulatory t cells playing a significant role.
The myeloid landscape transformation may influence how tumors respond to treatment, potentially affecting patient outcomes.
Mouse models of lung tumors show distinct changes in myeloid cells following chemotherapy, providing insights into immune responses.
Understanding these dynamics could lead to improved strategies in managing lung tumors, especially post-chemotherapy.

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Implication

Chemotherapy alters the myeloid landscape in lung tumors, suggesting a role for regulatory t cells in tumor response.

Abstract

Chemotherapy changes the myeloid landscape in mouse lung tumors

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Cite This Study

Weber-Delacroix et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21ad9 https://doi.org/10.1158/2326-6066.30254984

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S2 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
2Figure S6 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
3Figure S5 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
4Figure S4 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
5Video S1 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
6Data from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
7Video S2 from Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors2025
8Supplementary Figure S2 from EML4–ALK Rearrangement Creates a Distinctive Myeloid Cell–Dominant Immunosuppressive Microenvironment in Lung Cancer2025