Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 2, 2025Clinical & Translational OncologyOpen Access

A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study

View Full Paper
Ask AI
Bookmark
Share

Authors

SSSonia ServitjaMCMaria Castro-HenriquesIÁIgnacio Álvarez

Discussion

Loading...

Member takes

Overview

Pilot randomized clinical study shows the formulation lowers CIPN incidence in hands, improving quality of life.

Key Points

  • A topical nociceutical formulation significantly reduced CIPN incidence in hands, improving patients' quality of life.
  • In the nociceutical group, 13% developed CIPN in hands compared to 32% in the moisturizing group, indicating effectiveness.
  • Participants using the nociceutical formulation experienced an increase in the number of chemotherapy cycles without CIPN symptoms.
  • Reduction of bothersome neuropathic symptoms was observed, with only 39% reporting issues compared to 60% using moisturizing cream.

Cite This Study

Servitja et al. (2025) studied this question.

synapsesocial.com/papers/68de8eaeaa6cec72c69ea8fahttps://doi.org/10.1007/s12094-025-04062-1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Oncologic Patients—A New Promise? Preliminary Results2025
  2. 2Topical menthol for chemotherapy-induced peripheral neuropathy: a randomised controlled trial in breast cancer2024 · 2 citations
  3. 3Temperature-controlled hand-foot cooling for prevention of chemotherapy-induced polyneuropathy (CIPN): Updated real-world data collection in 600 patients.2026
  4. 4Limb Compression Therapy and Chemotherapy‐Induced Peripheral Neuropathy in Women With Gynecologic Cancers: A Prospective Self‐Controlled Study( <scp>NEURO</scp> ‐ <scp>GLOVE</scp> Trial)2026
  5. 5Efficacy of Hand Cooling and Compression in Preventing Taxane-Induced Neuropathy2025 · 36 citations