R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 21

Key Points

• The vocal adoption of the target trial emulation framework by the US FDA suggests proactive engagement in health assessments.
• Key frameworks like the FRAME methodology systematically evaluate the use and impact of real-world evidence in regulatory submissions.
• The Canadian CanREValue framework is crucial for improving cancer medicine reassessment decisions with real-world evidence.
• Recent developments indicate a significant shift towards leveraging real-world evidence to enhance decision-making in health technology assessments.