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This is a In Vitro Study study.

October 3, 2025Clinical ChemistryOpen Access

A-404 Evaluating the need for head CT in mild TBI patients using a whole blood point-of-care test within 24 hours of suspected head injury

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Prospective analysis finds high sensitivity for ruling out trauma in mild TBI patients, indicating improved care pathways.

The i-STAT TBI test demonstrated a clinical sensitivity of 96.5% for detecting intracranial lesions in mild TBI patients.
Of 970 patients analyzed, 283 had positive CT imaging for acute traumatic lesions, confirming the test's effectiveness.
This point-of-care test assesses biomarkers GFAP and UCH-L1 using whole blood, enhancing evaluation speed and accuracy.
The findings highlight the potential to reduce unnecessary head CT scans and associated radiation exposure for mild TBI.

Smith et al. (2025) studied this question.

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