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October 3, 2025International Journal of Molecular SciencesOpen Access

Involvement of Vitamin D Receptor Gene Polymorphism in Increased Cardiovascular Risk Disease in the Algerian Population

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Authors

AGAssia GallezeFDFatma Zohra Djaballah-IderIGInès Gouaref

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Overview

This study finds a link between vitamin D receptor polymorphism and cardiovascular diseases in Algeria, suggesting implications for health risk assessment.

Key Points

  • Higher frequencies of the ApaI polymorphism were found in cardiovascular disease patients compared to controls.
  • CVD patients exhibited lower vitamin D levels and higher NT-proBNP levels based on their VDR genotype.
  • The presence of AA genotypes in the VDR gene may serve as a risk marker for heart failure within the population.
  • Data were obtained through the PCR-RFLP method and immunoassay techniques.

Cite This Study

Galleze et al. (2025) studied this question.

synapsesocial.com/papers/68e0450fa99c246f578b3ed4https://doi.org/10.3390/ijms26199627
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