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October 3, 2025Open Access

Supplementary Figure S2 from AHRR DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices

Yoshiki Tsuboi Hiroya Yamada Ryosuke Fujii Mirai Yamazaki Eiji Munetsuna Yoshitaka Ando Genki Mizuno Yuji Hattori Hiroshi Okumiyama Kensuke Murakami H Ishikawa Kyoichi Ohashi Koji Suzuki

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Key Points

Findings reveal that passive smoking is associated with altered AHRR DNA methylation levels, indicating potential cancer mortality risks.
Density plot illustrates significant changes in AHRR methylation among never smokers exposed to passive smoking.
Analysis conducted through detailed examination of supplementary figures related to AHRR methylation and cancer mortality.
These results highlight the need for considering passive smoking in cancer risk assessments, particularly in never smokers.

Implication

Analysis shows a correlation between passive smoking and AHRR DNA methylation levels in never smokers, suggesting overlooked cancer risks.

Abstract

Supplementary Figure S2 shows a density plot of AHRR DNAm levels by passive smoking among never smokers.

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Cite This Study

Tsuboi et al. (2025) studied this question.

synapsesocial.com/papers/68e24e65d6d66a53c247353d https://doi.org/10.1158/1055-9965.30271449

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S1 from <i>AHRR</i> DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices2025
2Supplementary Figure S3 from <i>AHRR</i> DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices2025
3Supplementary Figure S5 from <i>AHRR</i> DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices2025
4Supplementary Figure S4 from <i>AHRR</i> DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices2025
5Data from <i>AHRR</i> DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices2025

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