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October 5, 2025Critical Reviews in Food Science and Nutrition

Glial cell nutrient sensing: mechanisms of nutrients regulating Alzheimer’s pathogenesis and precision intervention

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Authors

QYQing YanQQQiushi QinSZShu Zhang

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Overview

This review uncovers how nutrients modulate glial cell functions in Alzheimer's disease, implying new intervention strategies.

Key Points

  • Nutrient alterations impact glial cells, which directly influence the pathogenesis of Alzheimer's disease.
  • Essential nutrients significantly affect brain energy metabolism and inflammatory responses linked to Alzheimer's.
  • A novel framework connects essential nutrients to specific glial cell functions, potentially guiding future interventions.
  • This review details dietary patterns and nutritional strategies aimed at preventing and managing Alzheimer's disease.

Cite This Study

Yan et al. (2025) studied this question.

synapsesocial.com/papers/68e28310dcef4a166ce03cf3https://doi.org/10.1080/10408398.2025.2568606
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epigenetic modulations and nutrient interactions in Alzheimer's disease: unveiling potential therapeutic pathways2025
  2. 2Neuroinflammation and nutrition in Alzheimer’s disease2025
  3. 3Targeting glial dysfunction in Alzheimer’s disease: insights into pathogenesis and emerging therapeutics2025 · 4 citations
  4. 4Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors2026
  5. 5Nut consumption as a therapeutic strategy to preserve brain function, attenuate neuropathology, and modulate cross-tissue microRNAs in a mouse model of Alzheimer's disease2026