A photocatalyst‐free photoinduced radical difluoromethylation approach for the convenient synthesis of difluoromethylated oxindoles from N ‐arylacrylamides with difluoromethyl phenoxathiinium salt (PT‐CF 2 H + BF 4 − ) was developed, this transformation involves radical difluoromethylation/cyclization cascade process and features photocatalyst‐free, mild reaction conditions, broad substrate scope and good functional groups tolerance. With this method, a wide variety of N ‐arylacrylamides were successfully converted to desired difluoromethylated oxindoles in good to excellent yields.
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Long et al. (2024) studied this question.
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