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September 9, 2024CureusOpen Access

Optimized Methodology to Produce Platelet-Rich Plasma and Perform Platelet Aggregation in Patients With Coronary Artery Disease

Atul Kashyap Bonu Saikrishna Bhanu Duggal

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Abstract

Inter-individual differences in clopidogrel metabolism and platelet counts within platelet-rich plasma (PRP) intrigued us to optimize light transmittance aggregometry (LTA) assay in coronary artery disease (CAD) patients administered with clopidogrel and ticagrelor. The objective of the study was to optimize PRP preparation using separating gel PRP tubes to perform LTA among CAD patients on clopidogrel and ticagrelor.

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Kashyap et al. (2024) studied this question.

synapsesocial.com/papers/68e590efb6db64358752c75b https://doi.org/10.7759/cureus.69032

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