Experimental study demonstrates angiosome-guided perfusion decellularization of fasciocutaneous flaps, highlighting a route to produce acellular matrices with intact vessels.
Tissue engineering based on whole-organ perfusion decellularization has successfully generated small-animal organs, including the heart and limbs. Herein, we aimed to use angiosome-guided perfusion decellularization to develop an acellular fasciocutaneous flap matrix with an intact vascular network.
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Yang et al. (2024) studied this question.
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