Figure 2 from Mast Cell Infiltration and Subtype Promote Malignant Transformation of Oral Precancer and Progression of Oral Cancer

A, Cox regression analysis of an independent OLK dataset GSE26549 showed that the conversion of the resting to activated MC infiltration increased the risk of malignant transformation to OSCC. B, Cox regression analysis of the OSCC dataset GSE41613 showed that increased activated MC infiltration was associated with poor overall survival and C, cancer-specific survival in OSCC. Cox regression analysis of the TCGA HNSC cohort showed that increased activated MC infiltration was associated with D, poorer overall survival and E, cancer-specific survival in HNSC.