Nasal Histoplasmosis in an Immunocompetent Patient - A Case Report

The clinical case described below deals with the diagnosis and treatment of a fungal infection in the nasal region, rare in immunocompetent patients and with few reports in the literature. A 49-year-old woman from the south of Brazil, with no previous comorbidities, began to suffer from swelling in the right nasal and orbital region for around 4 weeks, accompanied by intense pain, fever and drainage of purulent secretion from the nostril. The first biopsy was inconclusive, but subsequent biopsies led to the identification of a fungal infection and finally the diagnosis of histoplasmosis. Treatment with antifungal drugs was then started, which consequently allowed the condition to improve after several hospitalizations.