We show the first examples of one-pot, tandem sulfamoylation/aza-Michael reactions for the preparation of oxathiazinane heterocycles from linear alkenyl alcohol precursors. Our optimized protocols are tolerant of a variety of functional groups and provide products which are amenable for further transformations. The reactions scale well, and no special precautions are required to exclude air or ambient moisture.
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Sathyamoorthi et al. (2024) studied this question.
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