Figure 3 from Spatial Landscape of Malignant Pleural and Peritoneal Mesothelioma Tumor Immune Microenvironments

Immune cell phenotypes associated with clinical features. A, Prevalence of all cell types in MPM epithelioid (n = 45), biphasic (n = 16), and sarcomatoid (n = 7) subtypes (left) and MPeM epithelioid (n = 12) and biphasic (n = 3) subtypes (right) presented as the proportion of total cells. Statistical analysis was performed using one-sided Multiple Mann–Whitney nonparametric U tests. *, P < 0.05. B, Bubble plot illustrating significance levels, in which circle size corresponds to the level of significance, and circle color indicates which of the two comparisons on the y-axis shows higher levels of the cell type plotted on the x-axis. C, Box plots displaying cell-type proportion across different clinical subgroups in patients with MPM and MPeM. Statistical analysis was conducted using one-sided multiple Mann–Whitney U tests. P < 0.05 was considered significant. The center of the box plot represents the median, with the box boundaries indicating the 25th and 75th percentiles. Whiskers extend to the minimum and maximum values in the dataset.