Alterations of brain motion in idiopathic intracranial hypertension (IIH) based on amplified MRI (aMRI)

Heartbeat-driven brain motion has historically remained limited to the domain of research. Such motion may provide a window to characterise parenchymal and CSF pressures where direct, invasive measurements are disruptive and difficult to justify. Amplified MRI (aMRI) is a recently developed method which amplifies subtle brain motion. We show preliminary data that aMRI can be used to detect changes in brain motion associated with increased intracranial pressure in idiopathic intracranial hypertension (IIH), suggesting a potential non-invasive method for evaluating pressure levels of the subarachnoid space in patients with altered intracranial pressure.