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We hypothesized that the Look-Locker (LL) effect can label arterial spins without the need for subtraction between different inversion schemes. We developed a multiple-flip-angle, non-selective-inversion MR multitasking brain scan to produce co-registered T1, B1+, and perfusion-weighted maps. Flow-sensitive LL fitting homogenized B1+ maps and produced flow maps combining features of time-of-flight angiography images and PCASL perfusion-weighted images. GM/WM flow ratios were similar to PCASL and the literature range.
Serry et al. (Wed,) studied this question.
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