Characteristics of brain white matter network in adolescent patients with first-episode non-suicidal self-injury

Objective: Explore the characteristics of brain white matter network in non-suicidal self-injury patients. Methods: The diffusion tensor imaging were prospectively collected form 30 adolescent patients with NSSI. The data was processed by software. Two independent sample t-test and partial correlation analysis were used to compare network metrics and clinical symptoms. Results: There was no significant difference in global network metrics, but there were significant differences in nodal network metrics, including nodal efficiency, nodal degree centrality and nodal shortest path length (all P＜0.05). Conclusion: These finding provide new insights into the neural circuit mechanism of adolescent NSSI patients.