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A recent consensus recommends MOLLI-type methods for T1-mapping in the kidney, but these are slow due to the need for full relaxation between inversions. Acceleration can be easily achieved on routine MOLLI-sequences by repeating preparation pulses before complete relaxation, but this requires more accurate signal modelling. Here we propose a broadly applicable model-based approach which inverts a signal model built on Bloch simulations of magnetisation propagation. The method is validated on phantom data and a two-centre cohort of 50 patients with diabetic kidney disease.
Periquito et al. (Wed,) studied this question.
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