The bias and precision of T2 and T2* estimates for a five-echo GESE model were studied using CRLB and Monte Carlo simulations. Different SNR cases were implemented by varying the standard deviation of added noise or the T2/T2* ratio. An in-vivo study with high SNRs for all EPI readouts was performed to validate the simulation.
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Huang et al. (2024) studied this question.
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