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August 12, 2024CureusOpen Access

Evaluation of the Phytochemical Screening of Methanolic Seed Extracts of Tribulus terrestris: An In Vitro Application of Anti-cancer, Anti-oxidant, and Anti-microbial Activities

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Authors

MMMohammed Yaseen MalikAAArockia AlexASAzhagu Madhavan Sivalingam

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Overview

In vitro study demonstrates cytotoxicity and antioxidant activity of Tribulus terrestris seed extract in oral cancer cells, highlighting therapeutic potential.

Key Points

  • Methanolic seed extracts of Tribulus terrestris suppress oral cancer cells in a concentration-dependent manner while providing broad antioxidant protection.
  • Growth inhibition reaches significant levels at 100 μg/mL during the MTT assay, while free radical scavenging correlates positively with total phenolic content.
  • Assessment of pro-apoptotic induction highlights therapeutic potential against oral cancer cells, though in vitro cell models warrant further preclinical validation.

Cite This Study

Malik et al. (2024) studied this question.

synapsesocial.com/papers/68e5ca72b6db643587561001https://doi.org/10.7759/cureus.66674
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Also Consider

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  1. 1Integration of in silico and in vitro approaches to evaluate antioxidant and anticancer properties of Tribulus terrestris extracts2022 · 10 citations
  2. 2Bioactive Compounds, Antibacterial, Antioxidant, Anticancer, and Antidiabetic Potential of the Seed and Leaves of Tribulus terrestris2025
  3. 3Bioactive Compounds, Antibacterial, Antioxidant, Anticancer, and Antidiabetic Potential of the Seed and Leaves of Tribulus terrestris2025
  4. 4Evaluation of The Antimicrobial, Antioxidant, and Other Biological Activities of Tribulus terrestris Plants Collected From Different Countries2024
  5. 5Phytochemical analysis and antibacterial activity of Tribulus terrestris L. against selected bacterial strains2026