Figure 6 from Exosomal Thomsen–Friedenreich Glycoantigen: A New Liquid Biopsy Biomarker for Lung and Breast Cancer Diagnoses

ROC analysis to evaluate diagnostic performance of exosomal TF-Ag-α in breast cancer. ROC curves of comparisons between all patients with breast cancer (n = 70) and normal controls (n = 29; A); nonmetastatic breast cancer (stages 0–III, n = 55) and normal controls (n = 29; B); metastatic breast cancer (stage IV, n = 15) and normal controls (n = 29; C); luminal A/B breast cancer (n = 44) and normal controls (n = 29; D); triple-negative breast cancer (n = 9) and normal controls (n = 29; E); and HER2-positive breast cancer (n = 17) and normal controls (n = 29; F). The sensitivity (SEN), specificity (SPE), AUC, and cutoff values of exosomal TF-Ag-α for each comparison are summarized in G.