Neonatal lupus erythematosus with severe persistent pulmonary hypertension

Learning points for cliniciansNeonatal lupus erythematosus (NLE) is a rare acquired autoimmune disease associated with maternal anti-Sj€ ogren syndrome-related antigen A (Ro), anti-Sj€ ogren syndromerelated antigen B (La) and anti-ribonucleoprotein antibodies, characterized by cutaneous manifestations and congenital heart block, hepatic dysfunction and hematological abnormalities.Herein, we reported a case of NLE with severe persistent pulmonary hypertension of the newborn as the primary manifestation.