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July 9, 2024Chinese Medical JournalOpen Access

Lactate aggravates inflammation through the upregulation of ICAM-1 via GPR81-HSPA12B-mediated signaling in acute lung injury

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Authors

WCWei ChangXLXu LiuHWHaofei Wang

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Chang et al. (2024) studied this question.

synapsesocial.com/papers/68e60e4db6db6435875a1439https://doi.org/10.1097/cm9.0000000000003153
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Also Consider

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  1. 1Glycolysis drives vascular hyperpermeability in acute lung injury via lactate-GPR81 axis in endothelial cells2026
  2. 2<scp>GPR81</scp> Activation by Lactate Delays Inflammation Resolution in Acute Lung Injury2026 · 1 citations
  3. 3A104-16 Lactylation of SRSF4 at K95 Promotes Acute Lung Injury via Alternate Splicing of SMPD12026
  4. 4YY1 lactylation mediates epithelial barrier dysfunction during acute lung injury2026
  5. 5Protective role of lactate in allergic airway inflammation: mitigation of inflammatory injury, epithelial barrier integrity restoration, and gut-lung axis involvement2026