July 5, 2024CureusOpen Access

Exploring the Role of Th10 Cells and IL-10 in Systemic Lupus Erythematosus

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Review reveals conflicting inflammatory activities of interleukin-10 in systemic lupus erythematosus, highlighting complex immune regulation.

Interleukin-10 acts as a pleiotropic cytokine with conflicting roles in inflammation, while systemic lupus erythematosus involves autoantibody production.
Systemic lupus erythematosus manifests through immune complex deposition in multiple organs, driven by genetic, hormonal, environmental, and immune factors.
Understanding the regulatory functions of th10 cells and interleukin-10 may clarify immune pathology, guiding future targeted autoimmune interventions.

Verma et al. (2024) studied this question.

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Review reveals conflicting inflammatory activities of interleukin-10 in systemic lupus erythematosus, highlighting complex immune regulation.