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July 1, 2024Translational Cancer ResearchOpen Access

The ratio of PKM1/PKM2 is the key factor affecting the glucose metabolism and biological function of colorectal cancer cells

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Authors

LMLiang MaXZXue ZhangYLYan Liu

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Cite This Study

Ma et al. (2024) studied this question.

synapsesocial.com/papers/68e62387b6db6435875b600bhttps://doi.org/10.21037/tcr-24-154
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE PKM2 PYRUVATE KINASE ISOFORM: THE BASIC AND TRANSLATIONAL ASPECTS IN THE CONTEXT OF THE MOLECULAR DIAGNOSIS OF HUMAN MALIGNANCIES2025
  2. 2Pyruvate Kinase M2: Function, Regulation and Targeting Therapeutics In Cancer2026
  3. 3Targeting PKM2 in cancer therapeutics: mechanistic advances and translational opportunities2025 · 7 citations
  4. 4Prognostic Value of PKM2 Expression in de novo Metastatic Colorectal Cancer Patients2025 · 1 citations
  5. 5PKM2 phosphorylation by c-SRC activates glycolysis and metastasis with the stimulation of tumor-associated macrophages2026