June 27, 2024Frontiers in GeneticsOpen Access

Lactylation: The emerging frontier in post-translational modification

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Authors

LZLu ZhouFudan University XZXueting ZhengInner Mongolia Agricultural University MSMingsong ShiUniversity of Electronic Science and Technology of China

Discussion

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Implication

Review outlines the mechanisms of protein lactylation across diverse organisms, highlighting its regulatory roles in inflammation, tumor proliferation, and metabolism.

Key Points

Lactylation functions as a key post-translational modification derived from lactate, regulating critical processes like inflammation, embryonic development, and metabolism.
Review of cellular pathways characterizes protein lactylation across diverse organisms, detailing regulatory mechanisms that control tumor proliferation and metabolism.
Highlights persistent mechanistic gaps in how lactylation regulates disease contexts, calling for targeted future investigations to clarify its precise role in inflammation.

Cite This Study

Zhou et al. (2024) studied this question.

synapsesocial.com/papers/68e62ea5b6db6435875c14b7 https://doi.org/10.3389/fgene.2024.1423213

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June 27, 2024Frontiers in GeneticsOpen Access

Lactylation: The emerging frontier in post-translational modification

View Full Paper

Ask AI

Bookmark

Authors

LZLu ZhouFudan University XZXueting ZhengInner Mongolia Agricultural University MSMingsong ShiUniversity of Electronic Science and Technology of China

Discussion

Member takes

Implication

Review outlines the mechanisms of protein lactylation across diverse organisms, highlighting its regulatory roles in inflammation, tumor proliferation, and metabolism.

Key Points

Lactylation functions as a key post-translational modification derived from lactate, regulating critical processes like inflammation, embryonic development, and metabolism.
Review of cellular pathways characterizes protein lactylation across diverse organisms, detailing regulatory mechanisms that control tumor proliferation and metabolism.
Highlights persistent mechanistic gaps in how lactylation regulates disease contexts, calling for targeted future investigations to clarify its precise role in inflammation.

Cite This Study

Zhou et al. (2024) studied this question.

synapsesocial.com/papers/68e62ea5b6db6435875c14b7 https://doi.org/10.3389/fgene.2024.1423213

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