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June 18, 2024International Immunology

Regulation of memory CD4+ T-cell generation by intrinsic and extrinsic IL-27 signaling during malaria infection

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Authors

STSanjaadorj TsogtsaikhanSIShinichi InoueGBGanchimeg Bayarsaikhan

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Cite This Study

Tsogtsaikhan et al. (2024) studied this question.

synapsesocial.com/papers/68e643e9b6db6435875d5bf9https://doi.org/10.1093/intimm/dxae039
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CD4 T Cell–Derived IL-21 Is Critical for Sustaining <i>Plasmodium</i> Infection–Induced Germinal Center Responses and Promoting the Selection of Memory B Cells with Recall Potential2024 · 3 citations
  2. 2Endogenous IL-27 during toxoplasmosis limits early monocyte responses and their inflammatory activation by pathological T cells2024 · 15 citations
  3. 3IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion2025
  4. 4IL-15 enhances T resident memory formation and function following genetically attenuated Plasmodium vaccination in mice 32322025
  5. 5Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms2024