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June 14, 2024Naunyn-Schmiedeberg s Archives of PharmacologyOpen Access

Sorafenib and edaravone protect against renal fibrosis induced by unilateral ureteral obstruction via inhibition of oxidative stress, inflammation, and RIPK-3/MLKL pathway

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Authors

MTMohamed A. Abou TahaFAFares E.M. AliISIbrahim G. Saleh

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Taha et al. (2024) studied this question.

synapsesocial.com/papers/68e64b2fb6db6435875dbd93https://doi.org/10.1007/s00210-024-03146-z
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren2010 · 62 citations
  2. 2The Sirt1 activator, SRT1720, attenuates renal fibrosis by inhibiting CTGF and oxidative stress2017 · 106 citations
  3. 3Co-inhibition of Angiotensin II Receptor and Endothelin-1 Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice2016 · 13 citations
  4. 4Effect of Angiotensin II and Small GTPase Ras Signaling Pathway Inhibition on Early Renal Changes in a Murine Model of Obstructive Nephropathy2014 · 15 citations
  5. 5Dual soluble epoxide hydrolase inhibitor – farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis2024 · 5 citations