Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 8, 2025Frontiers in EpidemiologyOpen Access

Carotid artery atherosclerosis, MRI-defined structural brain abnormalities, and cognitive performance in elderly American Indians: The Strong Heart Study

View Full Paper
Ask AI
Bookmark
Share

Authors

TATauqeer AliOklahoma City UniversityDBDedra BuchwaldWashington State University SpokaneDSDean ShibataUniversity of Washington

Discussion

Loading...

Member takes

Implication

This study explores links between carotid atherosclerosis, brain abnormalities, and cognitive outcomes in American Indian adults, highlighting potential risks.

Key Points

  • Increased intima-media thickness correlates with greater brain atrophy, indicating risks to cognitive health.
  • Presence and extent of carotid plaque relate to poorer verbal fluency, supporting links between vascular health and cognition.
  • Longitudinal data from the Strong Heart Study informs potential interventions for cognitive health in underserved populations.
  • Adjustments for sociodemographic and clinical factors enhance the reliability of findings regarding brain health.

Cite This Study

Ali et al. (2025) studied this question.

synapsesocial.com/papers/68e6679587ecc93a24d175e6https://doi.org/10.3389/fepid.2025.1659856
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Carotid Intima–Media Thickness and Markers of Brain Health in a Biracial Middle-Aged Cohort: CARDIA Brain MRI Sub-study2019 · 27 citations
  2. 2Vascular Biomarkers in the Prediction of Clinical Cardiovascular Disease2011 · 59 citations
  3. 3Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study2017 · 22 citations
  4. 4Psychometric Reliability, Validity, and Generalizability of MoCA in American Indian Adults: The Strong Heart Study2024 · 6 citations
  5. 5Parallel cardiac and vascular adaptation in hypertension.1992 · 365 citations