Central Giant Cell Granuloma of Maxilla.

Background: Central giant cell granuloma are rare non-neoplastic lesions. They are histologically different from giant cell tumour of bone. It contains cellular brous tissue with multiple haemorrhagic foci with aggregates of multinucleated giant cells. Sometimes trabeculae of woven bone may also be seen. It was rst described by Jaffe in 1953 as an idiopathic non-neoplastic proliferative lesion. It is benign, intraosseous lytic lesion which has debatable aetiology. It doesn't have characteristic clinical and radiographical features which can help it to be distinguished from other lesions in this region. HPE analysis still remains the gold standard for identifying this disorder. Case presentation: A 19-year-old male patient presented to the author's centre with a swelling on upper jaw of his face on right side for 6 months along with tooth pain. External examination revealed a diffuse swelling over his right maxilla extending till the infraorbital region causing upliftment of the base of the nose. There is associated obliteration of the right nasolabial fold and causing facial asymmetry. There was missing 32 teeth with bony expansion in right vestibular region extending from rst molar till central incisor on right. There was a large expansile soft tissue density lesion seen arising from the maxilla on right side causing cortical thinning and breach measuring approximately 4.2 x 6.5 x 5.1 cm (AP X ML X CC). Multiple bony septations are seen within the lesion with discontinuous peripheral calcications. Based on the clinical and radiological presentation, a provisional diagnosis of an odontogenic cyst was made. Histopathological examination revealed normal cortical bone with a normal inamed cellular stroma with patchy distribution of multinucleated giant cells suggestive of giant cell granuloma. Conclusions: Surgical management of the patient was done with resection of the lesion and primary reconstruction with bone graft. The result of the surgery was successful.