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Background: Primary liposarcoma of the mediastinum accounts for less than 1% of all mediastinal tumors and 2% of all liposarcomas, making them exceedingly rare. When they do occur, they typically originate in the posterior mediastinum. These tumors are slow growing, and thus are found incidentally or present later in the course with compressive symptoms.
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Heutlinger et al. (2024) studied this question.
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