May 17, 2024Dermatology and TherapyOpen Access

Evaluation of the Factors Influencing Mortality in Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Study of 166 Patients

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Authors

FEFunda ErduranBilkent University EAEsra AdışenGazi Hastanesi SESelma EmreAnkara University

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Implication

Retrospective cohort study reveals that elevated SCORTEN scores and plasmapheresis predict increased mortality in Stevens-Johnson syndrome and toxic epidermal necrolysis, indicating urgent risk...

Key Points

Mortality in Stevens-Johnson syndrome and toxic epidermal necrolysis rose sharply with higher severity, reaching an overall exitus rate of 24.1%.
A SCORTEN score of 5–6 increased mortality odds 84-fold compared to scores of 0–1, whereas plasmapheresis showed a 22-fold increase in mortality.
Retrospective cohort study across 12 tertiary care centers tracked 166 patients receiving supportive care along with systemic steroids and IVIG.
Highlights the strong prognostic value of early SCORTEN scoring, while showing that common immunomodulatory therapies had no impact on mortality.

Cite This Study

Erduran et al. (2024) studied this question.

synapsesocial.com/papers/68e69859b6db64358761ea56 https://doi.org/10.1007/s13555-024-01180-6

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Implication

Retrospective cohort study reveals that elevated SCORTEN scores and plasmapheresis predict increased mortality in Stevens-Johnson syndrome and toxic epidermal necrolysis, indicating urgent risk...

Evaluation of the Factors Influencing Mortality in Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Study of 166 Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Evaluation of the Factors Influencing Mortality in Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Study of 166 Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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