Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 13, 2026Journal of Cutaneous Medicine and Surgery

Incidence and Factors Associated With In-Hospital Mortality in Adult Patients With Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Nationwide Thai Cohort

View Full Paper
Ask AI
Bookmark
Share

Authors

RWRachot WongjirattikarnCCCharoen ChoonhakarnSCSuteeraporn Chaowattanapanit

Discussion

Loading...

Member takes

Overview

Retrospective cohort study estimates in-hospital mortality in Thailand, indicating evolving risk factors over time.

Key Points

  • To estimate the incidence and identify factors associated with in-hospital mortality in adults with SJS/TEN in Thailand.
  • Conducted a retrospective cohort study using the Thai National Health Security Office database.
  • Identified hospitalized adults with SJS/TEN using ICD-10 codes from 2017 to 2024.
  • Employed Cox regression with time-varying coefficients to analyze mortality risk factors.
  • Identified 7237 incident cases of SJS/TEN (83.9% SJS) with an overall incidence of 17.3/million.
  • In-hospital mortality rates were 4.1% for SJS and 15.5% for TEN.
  • Factors significantly influencing mortality included invasive ventilation (HR 14.99), liver disease (HR 2.49), renal disease (HR 2.46), and age ≥60 years.

Cite This Study

Wongjirattikarn et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf701faef96ed7f058a11https://doi.org/10.1177/12034754261455749
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In-hospital outcomes of SJS/TEN cases in a tertiary center: a 15-year cohort study2026
  2. 2Evaluation of the Factors Influencing Mortality in Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Study of 166 Patients2024 · 9 citations
  3. 3Analysis of the clinical characteristics and prognostic influencing factors of toxic epidermal necrolysis: A report of 52 cases2025
  4. 4Profile And Risk Factors of Stevens Johnson Syndrome–Toxic Epidermal Necrolysis on Adult Patients in Dr. Moewardi General Hospital Surakarta from January 2019 – December 20222024
  5. 5The Outcomes of SJS/TEN: A Nationwide Analysis2026