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May 2, 2024Proceedings of the National Academy of SciencesOpen Access

BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes

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Authors

LBLong BaiPLPeng LiYXYu Xiang

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Bai et al. (2024) studied this question.

synapsesocial.com/papers/68e6bbe0b6db64358763ccf9https://doi.org/10.1073/pnas.2401386121
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Functions and mechanisms of BRCA1 in early embryonic development2026
  2. 2BRCA1/BRC-1 and SMC-5/6 regulate DNA repair pathway engagement during Caenorhabditis elegans meiosis2024 · 5 citations
  3. 3Abstract 1850 The Association between Tumor Suppressor BRCA2 and DNA in Maintaining Genome Integrity2024
  4. 4Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation2024 · 1 citations
  5. 5BRCA1 is an essential regulator of heart function and survival following myocardial infarction2011 · 156 citations