O-partial least-squares discrimination analysis (OPLS-DA) of metabolites of Cohort 1 and Cohort 2 under negative (A, C) and positive (B, D) ion modes. Identified compounds could be separated well with optimal goodness of fit. Green indicates samples from the long-term survival group; blue indicates samples from the short-term survival group.
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Xu et al. (2024) studied this question.
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