Figure S2 from Evaluating for Correlations between Specific Metabolites in Patients Receiving First-Line or Second-Line Immunotherapy for Metastatic or Recurrent NSCLC: An Exploratory Study Based on Two Cohorts

Volcano plot of serum metabolomics in Cohorts 1 and 2. The left figures (A, C) were obtained in the negative polarity mode, and the right figures (B, D) were obtained in the positive polarity mode. The abscissa is the log value of log2 of multiple differential expression (fold change), and the ordinate is the log value of -log10 of significant p values. Significant different metabolites: those with an FC> 1.5 and p value <0.05 are shown in rose red, and those with an FC <0.67, and p value <0.05 are colored in blue. Nonsignificantly different metabolites are indicated in black.