A-41 | Coronary Artery Anomalies Does Not Predict Worse Outcomes for ST-elevation Myocardial Infarction

Coronary Artery Anomalies (CAA) are a group of congenital conditions characterized by an abnormal origin or source of coronary arteries, and are often identified in young patients after sudden cardiac death. Despite their increasing recognition during coronary imaging, these conditions remain relatively rare, and the prognostic implications of incidental CAA are not yet clear. Our study aims to assess the impact of CAA on the in-hospital outcomes of patients with ST-elevation myocardial infarction (STEMI). We identified all admissions with a principal diagnosis of STEMI, with and without CAA, from the National Inpatient Sample Database from 2016-2020 using ICD-10 codes. Primary outcome was inpatient mortality. Secondary outcomes are shown in Table 1. Multivariate regression analysis was used to adjust for potential confounders. Out of 1,715,130 STEMI admissions, 6,695 (0.40%) admissions had CAA. Compared to those without CAA, patients with CAA were more likely to be younger (64.2 years vs 60.5 years), male (67.6% vs 72.2%) with lower burden of co-morbidities such as hypertension (73.9% vs 66.8%), diabetes mellitus (33.2% vs 25.1%), chronic kidney disease (15.3% vs 8.59%), heart failure (38.5% vs 29.6%), and chronic lung disease (16.7% vs13.9%). After adjusting for confounders, both groups had similar mortality, complication rates, length of stay and total charges as shown in Table 1. CAA does not predict worse outcomes in patients presenting with STEMI. However, additional research should aim to assess the impact of each specific type of CAA on STEMI outcomes, as well as the impact on other cardiac conditions.