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May 1, 2024Physiology

Characterization of cardiac fibrosis in older lean vs. obese male ZSF1 rats

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CMCaitlyn MooersWPWrenn D PallasJHJohanna L. Hannan

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Mooers et al. (2024) studied this question.

synapsesocial.com/papers/68e6c6ffb6db643587645ef1https://doi.org/10.1152/physiol.2024.39.s1.1917
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Both male and female obese ZSF1 rats develop cardiac dysfunction in obesity-induced heart failure with preserved ejection fraction2020 · 60 citations
  2. 2ZSF1 Rat as Animal Model for HFpEF: Development of Reduced Diastolic Function and Skeletal Muscle Dysfunction2020 · 82 citations
  3. 3Arterial Remodeling and Dysfunction in the ZSF1 Rat Model of Heart Failure With Preserved Ejection Fraction2019 · 35 citations
  4. 4Distinct Endothelial Cell Responses in the Heart and Kidney Microvasculature Characterize the Progression of Heart Failure With Preserved Ejection Fraction in the Obese ZSF1 Rat With Cardiorenal Metabolic Syndrome2016 · 83 citations
  5. 5Abstract Wed082: Integrated Systems Biology Identifies Disruptions In Mitochondrial Function And Metabolism As Key Contributors To HFpEF2025