Efficacy of the Moxidectin and Spinosad Combination Against Canine Ixodidosis

The article presents the results of a study on acaricidal efficacy of the combination of Moxidectin and Spinosad, which are part of ExpressTabs®, in transfer of ixodid ticks on dogs. The study was carried out at the Animal Welfare Center of SVS-N LLC on 24 clinically healthy mixed breed dogs which were divided into two groups of 12 animals each: experimental (with ExpressTabs®) and control (the drug was not given). Acaricidal activity of the drug was determined in accordance with MG 3.5.2.1759-03. As a result of the studies, ExpressTabs® was found to be 100% effective against ixodidosis at 24 hours after the use. Two weeks after ExpressTabs®, 57.0, 95.8, and 100% efficacy was found against ixodidosis in the dogs at 24, 48, and 72 hours after tick transfer, respectively. Four weeks after ExpressTabs®, 57.8, 91.0, and 100% efficacy was found against ixodidosis in the dogs at 24, 48, and 72 hours after tick transfer, respectively. Six weeks after ExpressTabs®, 41.6, 77.1, and 91.5% efficacy was found against ixodidosis in the dogs at 24 hours, 48 hours, and 72 hours after tick transfer, respectively.