What question did this study set out to answer?

The study aims to confirm the efficacy of NexGard® Plus in treating dogs infested with Sarcoptes scabiei.

January 25, 2026

Field efficacy assessment of a combination of afoxolaner, moxidectin and pyrantel pamoate to treat dogs naturally infested with

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Authors

LALoïc AntoineBoehringer Ingelheim (United States)EPElias C. PapadopoulosAristotle University of Thessaloniki GSGeorgios SioutasAristotle University of Thessaloniki

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Implication

Clinical field study demonstrates effective treatment of canine sarcoptic mange in infested dogs, highlighting important implications for animal welfare.

Key Points

The study aims to confirm the efficacy of NexGard® Plus in treating dogs infested with Sarcoptes scabiei.
Blinded, randomized, single-centre, negative-controlled efficacy study
Twenty dogs naturally infested with S. scabiei divided into treatment and control groups
Skin scrapings conducted for mite counts and assessments of clinical signs at specific intervals
Mite infestations reduced by 97% after the first treatment and eliminated (100%) after the second (p < 0.0005)
Treated dogs showed no pruritus, papules, or crusts by Day 56
Control group remained infested throughout the study

Cite This Study

Antoine et al. (2026) studied this question.

synapsesocial.com/papers/6975b38dfeba4585c2d6f0ef https://doi.org/10.1051/parasite/2026001/pdf

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Implication

Clinical field study demonstrates effective treatment of canine sarcoptic mange in infested dogs, highlighting important implications for animal welfare.

Field efficacy assessment of a combination of afoxolaner, moxidectin and pyrantel pamoate to treat dogs naturally infested with

Discussion

Member takes

Implication

Key Points

Cite This Study

Field efficacy assessment of a combination of afoxolaner, moxidectin and pyrantel pamoate to treat dogs naturally infested with

Discussion

Member takes

Implication

Key Points

Cite This Study

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