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October 8, 2025

The Association Between Markers of Lipid Homeostasis, Inflammation, and Atherosclerosis Index in Patients with Type 2 Diabetes and Coronary Heart Disease Stratified by Glycemic Control: A Cross-Sectional Study.

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Authors

PYPing YangTDTian DaiLJLi Jiang

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Overview

Cross-sectional analysis shows glycemic control impacts lipid levels and inflammation in type 2 diabetes patients with CHD, highlighting cardiovascular risk factors.

Key Points

  • Poor glycemic control in type 2 diabetes patients associates with increased arterial stiffness and dyslipidemia, indicating elevated cardiovascular risk.
  • Increased atherosclerosis index (AI) and coronary stenosis scores observed in patients with poor glycemic control, suggesting critical health implications.
  • Key risk factors for elevated AI include inflammatory markers and lipid profiles, with hs-CRP and HOMA-IR serving as independent predictors.
  • Analysis emphasizes the need for a multifactorial approach to managing cardiovascular risk in high-risk groups like those with type 2 diabetes.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68e6d7971ffa7aa7d63d166ahttps://doi.org/10.2147/jir.s550135
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The importance of determining inflammatory parameters in patients with coronary artery disease and type 2 diabetes mellitus2025
  2. 2Atherogenic index of plasma and the severity of coronary artery stenosis in patients with type 2 diabetes mellitus: a retrospective cross-sectional study2026
  3. 3Coronary inflammation based on pericoronary adipose tissue attenuation in type 2 diabetic mellitus: effect of diabetes management2024 · 21 citations
  4. 4An Atherogenic Index of Plasma in Type 2 Diabetes Mellitus with and without Coronary Artery Disease2025 · 2 citations
  5. 5A study on the lipid ratios and inflammatory markers in pre-diabetic and diabetic patients2019 · 4 citations