Multimodal Imaging and Follow-Up of a Nodule arising from Congenital Hypertrophy of the Retinal Pigment Epithelium

Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE) is a benign ocular condition. Here, we present a rare case of a neoplasm arising from a CHRPE, diagnosed as retinal pigment epithelium (RPE) adenoma (epithelioma) or adenocarcinoma (malignant epithelioma). Utilizing multimodal imaging, we followed the lesion over a sixteen-month period, during which it showed stable size, absent exudation, and resolution of the overlying vitreous hemorrhage.