Plague therapy : Current and Future Strategies

Plague, caused by the bacterium Yersinia pestis, is a vector-borne disease that has led to millions of human deaths over the centuries.Today, human plague infections still occur Worldwide.Transmission typically happens Through bites from infected fleas, which cause swollen lymph nodes known as buboes and can Lead to septicemia.Inhaling droplets from close contact with infected animals can also cause Primary pneumonic plague.This review examines recent research advancements in plague vaccines and treatments, focusing on Y. pestis's Virulence factors and disease pathogenesis.Plague remains a significant public health and biodefense concern, emphasizing the need for ongoing research in infection prevention and treatment.