Pd53-05 Critical Differences in Semen and Urine Microbiome Manifest in Men With Abnormal Sperm Parameters

You have accessJournal of UrologyInfertility: Basic Research D. micraerophilus: r=0.44, p=0.014; Figure 1). Men with abnormal sperm concentration (N=20) showed a higher abundance of semen P. fluorescens (p=0.010) and semen P. stutzeri (p=0.024), but a lower abundance of semen P. putida (p=0.005), urine E. faecalis (p=0.012), and urine S. aureus (p=0.037), compared to men with normal sperm concentration (N=53). CONCLUSIONS: Our findings highlight a critical group of seminal and urinary microorganisms associated with abnormalities in sperm motility and concentration. These data support findings from previously published, smaller studies, while also providing target microorganisms for future mechanistic investigations into the complex relationship between the microbiome and male infertility. Download PPT Source of Funding: This work was supported in part by the 2023 Urology Care Foundation Residency Research Award Program and the Russell Scott, Jr., MD, Urology Research Fund © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1139 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Vadim Osadchiy More articles by this author Andre Belarmino More articles by this author Reza Kianian More articles by this author John T. Sigalos More articles by this author Thiago P. Furtado More articles by this author Jacob S. Ancira More articles by this author Trisha Kanie More articles by this author Sarah F. Magnum More articles by this author Craig D. Tipton More articles by this author Tung-Chin M. Hsieh More articles by this author Jesse N. Mills More articles by this author Sriram V. Eleswarapu More articles by this author Expand All Advertisement PDF downloadLoading ...