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April 9, 2024Neurology

Transcranial Doppler Bubble Study Technique in a Clinical Trial: Valsalva Maneuver and Body Position Matter but IV Location Does Not (S10.002)

Mark N. Rubin Ruchir Shah Teddy S. Youn John Volpi Aaron Stayman Theodore Lowenkopf Georgios Tsivgoulis Andrei V. Alexandrov

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Abstract

This is a secondary analysis of BUBL, a clinical trial (www.clinicaltrials.gov; NCT04604015), to ascertain the effects of transcranial Doppler (TCD) bubble study technique on results, including right to left shunt (RLS) presence and size.

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Cite This Study

Rubin et al. (2024) studied this question.

synapsesocial.com/papers/68e6fcc5b6db6435876773dc https://doi.org/10.1212/wnl.0000000000206376

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Goal-directed vs self-directed Valsalva manoeuvre to improve right to left shunt detection: the BUBBLE trialOriginal Research · 2026
2Contrast‐enhanced transcranial Doppler for the detection of right‐to‐left shunt: A new provocation method with a syringe‐modified Valsalva maneuver2024 · 2 citations
3Is Transcranial Doppler for the Detection of Venous-to-Arterial Circulation Shunts Reproducible?cross-sectional · 2007 · 48 citations
4Abstract TP007: Beyond Echocardiography: How Transcranial Doppler Transforms Right-to-Left Shunt Detection and Stroke Managementcohort · 2026
5Optimizing the Technique of Contrast Transcranial Doppler Ultrasound in the Detection of Right-to-Left Shuntscross-sectional · 2002 · 112 citations

More related papers

Controlled Contrast Transcranial Doppler and Arterial Blood Gas Analysis to Quantify Shunt Through Patent Foramen Ovale2004
Sensitivity of brachial versus femoral vein injection of agitated saline to detect right‐to‐left shunts with Transcranial Doppler2014
Novel robotic TCD ultrasound with bubbles versus standard care to detect right to left shunt: Study methods2021

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